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Test Code PNEFS Neuroimmunology Antibody Follow-up, Serum

Reporting Name

Neuroimmunology Ab Follow-up, S

Useful For

Monitoring patients who have previously tested positive for 1 or more antibodies in the Mayo Neuroimmunology Laboratory within the past 5 years.

 

Requests for the follow-up assay in serum specimens must have previously been positive in a serum evaluation.

Reflex Tests

Test ID Reporting Name Available Separately Always Performed
ARMO ACh Receptor (Muscle) Modulating Ab No No
GANG AChR Ganglionic Neuronal Ab, S No No
AMPCS AMPA-R Ab CBA, S No No
AMPIS AMPA-R Ab IF Titer Assay, S No No
AMPHS Amphiphysin Ab, S No No
ABLOT Amphiphysin Western Blot, S No No
AGN1S Anti-Glial Nuclear Ab, Type 1 No No
ANN1S Anti-Neuronal Nuclear Ab, Type 1 No No
ANN2S Anti-Neuronal Nuclear Ab, Type 2 No No
ANN3S Anti-Neuronal Nuclear Ab, Type 3 No No
CS2CS CASPR2-IgG CBA, S No No
CRMWS CRMP-5-IgG Western Blot, S No No
CRMS CRMP-5-IgG, S No No
GABCS GABA-B-R Ab CBA, S No No
GABIS GABA-B-R Ab IF Titer Assay, S No No
LG1CS LGI1-IgG CBA, S No No
VGKC Neuronal (V-G) K+ Channel Ab, S No No
NMDCS NMDA-R Ab CBA, S No No
NMDIS NMDA-R Ab IF Titer Assay, S No No
CCN N-Type Calcium Channel Ab No No
CCPQ P/Q-Type Calcium Channel Ab No No
WBN Paraneoplastic Autoantibody WBlot,S No No
PCABP Purkinje Cell Cytoplasmic Ab Type 1 No No
PCAB2 Purkinje Cell Cytoplasmic Ab Type 2 No No
PCATR Purkinje Cell Cytoplasmic Ab Type Tr No No

Method Name

ANN1S, ANN2S, ANN3S, AGN1S, PCABP, PCAB2, PCATR, AMPHS, CRMS, AMPIS, GABIS, NMDIS: Indirect Immunofluorescence (IFA)

AMPCS, GABCS, NMDCS, LG1CS, CS2CS: Cell-Binding Assay (CBA)

WBN, CRMWS, ABLOT: Western Blot

CCPQ, CCN, GANG, VGKC, ARMO: Radioimmunoassay (RIA)

Performing Laboratory

Mayo Medical Laboratories in Rochester

Specimen Type

Serum


Specimen Required


Container/Tube:

Preferred: Red top

Acceptable: Serum gel

Specimen Volume: 4 mL


Specimen Minimum Volume

2 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Refrigerated (preferred) 28 days
  Frozen  28 days
  Ambient  72 hours

Reject Due To

Hemolysis

Mild OK; Gross reject

Lipemia

Mild OK; Gross reject

Icterus

Mild OK; Gross reject

Other

NA

Reference Values

Test ID

Reporting Name

Reference Value

GANG

AChR Ganglionic Neuronal Ab, S

<0.02

AMPCS

AMPA-R Ab CBA, S

Negative

AMPIS

AMPA-R Ab IF Titer Assay, S

<1:120

AMPHS

Amphiphysin Ab, S

<1:240

ABLOT

Amphiphysin Western Blot, S

Negative

AGN1S

Anti-Glial Nuclear Ab, Type 1

<1:240

ANN1S

Anti-Neuronal Nuclear Ab, Type 1

<1:240

ANN2S

Anti-Neuronal Nuclear Ab, Type 2

<1:240

ANN3S

Anti-Neuronal Nuclear Ab, Type 3

<1:240

CS2CS

CASPR2-IgG CBA, S

Negative

CRMS

CRMP-5-IgG, S

<1:240

GABCS

GABA-B-R Ab CBA, S

Negative

GABIS

GABA-B-R Ab IF Titer Assay, S

<1:120

LG1CS

LGI1-IgG CBA, S

Negative

VGKC

Neuronal (V-G) K+ Channel Ab, S

<0.02

NMDCS

NMDA-R Ab CBA, S

Negative

NMDIS

NMDA-R Ab IF Titer Assay, S

<1:120

NMOTS

NMO/AQP4 FACS Titer, S

<1:5

CCN

N-Type Calcium Channel Ab

<0.03

CCPQ

P/Q-Type Calcium Channel Ab

<0.02

WBN

Paraneoplastic Autoantibody WBlot,S

Negative

PCABP

Purkinje Cell Cytoplasmic Ab Type 1

<1:240

PCAB2

Purkinje Cell Cytoplasmic Ab Type 2

<1:240

PCATR

Purkinje Cell Cytoplasmic Ab Type Tr

<1:240

Day(s) and Time(s) Performed

ANN1S, ANN2S, ANN3S, AGN1S, PCABP, PCAB2, PCATR, AMPHS, CRMS, AMPIS, GABIS, NMDIS: Monday through Friday; 11:30 a.m. and 8 p.m.; Saturday and Sunday 8 a.m.

AMPCS, GABCS, NMDCS. LG1CS, CS2CS: Monday through Friday; 6 a.m.

Paraneoplastic autoantibody Western blot confirmation, CRMP-5-IgG Western blot, Amphiphysin Western blot: Monday, Wednesday, Friday; 8 a.m.

CCPQ, CCN, GANG, VGKC: Monday through Friday 11 a.m. and 6 p.m.; Saturday 6 a.m.; Sunday 6 a.m.

ACh receptor (muscle) modulating antibodies: Monday through Thursday, Saturday; 12 p.m., Saturday; 8 a.m.

Test Classification

Manually Entered

CPT Code Information

83519-59-ACh receptor (muscle) modulating antibodies (if appropriate)

83519-59-AChR ganglionic neuronal antibody (if appropriate)

83519-59-N-type calcium channel antibody (if appropriate)

83519-59-P/Q-type calcium channel antibody (if appropriate)

83519-VGKC (if appropriate)

84182-CRMP-5-IgG Western blot (if appropriate)

84182-Paraneoplastic autoantibody Western blot confirmation (if appropriate)

86255-Amphiphysin (if appropriate)

86255-ANNA-1 (if appropriate)

86255-ANNA-2 (if appropriate)

86255-ANNA-3 (if appropriate)

86255-CRMP-5-IgG (if appropriate)

86255-PCA-1 (if appropriate)

86255-PCA-2 (if appropriate)

86255-PCA-Tr (if appropriate)

86255-NMDCS (if appropriate)

86255-AMPCS (if appropriate)

86255-GABCS (if appropriate)

86256-NMDIS (if appropriate)

86256-AMPIS (if appropriate)

86256-GABIS (if appropriate)

86255-LG1CS (if appropriate)

86255-CS2CS (if appropriate)

LOINC Code Information

Test ID Test Order Name Order LOINC Value
PNEFS Neuroimmunology Ab Follow-up, S In Process

 

Result ID Test Result Name Result LOINC Value
84300 Neuroimmunology Ab Follow-up, S In Process

Forms

If not ordering electronically, complete, print, and send a Neurology Specialty Testing Client Test Request (T732) with the specimen (http://www.mayomedicallaboratories.com/it-mmfiles/neurology-request-form.pdf)